Effects of Sleep Deprivation & Exercise on Food Allergy Reactions

As reported in the Journal of Allergy and Clinical Immunology,  team of UK researchers administered an estimated threshold dose of peanut in a blind challenge. Then participants with a confirmed allergy “underwent 3 open peanut challenges in random order: with exercise after each dose, with sleep deprivation preceding challenge, and with no intervention.” They concluded: Exercise and sleep deprivation each significantly reduce the threshold of reactivity in patients with peanut allergy, putting them at greater risk of a reaction. Adjusting reference doses using these data will improve allergen risk management and labeling to optimize protection of consumers with peanut allergy.